Drugs & Vitamins

Active Ingredients: Adapalene
Other Names: Differin Topical Cream
Drug Class: Retinoids, Topical
Rx Status: Available by prescription only
Generic Available: No
Product Images & Descriptions:

What is/are Differin Topical Cream? (Back to top)
ADAPALENE is applied to the skin to treat mild to moderate acne. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine? (Back to top)
They need to know if you have any of these conditions:

• eczema
• seborrheic dermatitis
• skin abrasions
• sunburn
• an unusual or allergic reaction to adapalene, vitamin A, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine? (Back to top)
This medicine is for external use only, do not take by mouth. Follow the directions on the prescription label. Make sure the skin is clean and dry. Apply just enough to cover the affected area. Rub in gently. Do not get in the eyes, inside the nose, on wounds, or any other sensitive areas of skin.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose? (Back to top)
If you miss a dose, skip that dose and continue with your regular schedule. Do not use extra doses, or use for a longer period of time than directed by your doctor or health care professional.

What may interact with this medicine? (Back to top)

• topical antibiotics like clindamycin or erythromycin

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine? (Back to top)
Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• severe burning, reddening, crusting, or swelling of the treated areas

• inflamed, stinging, and irritated skin
• skin that peels after a few days of use

This list may not describe all possible side effects.

What should I watch for while using this medicine? (Back to top)
Your acne may get worse at first, and then should start to get better. It may take 2 to 12 weeks before you see the full effect.

Do not wash your face more than 3 times a day unless your doctor or health care professional tells you to. Do not use products that may dry the skin like medicated cosmetics, products that contain alcohol, or abrasive soaps or cleaners. Do not use other acne or skin treatment on the same area that you use this medicine unless your doctor or health care professional tells you to. If you use these together they can cause severe skin irritation.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Where should I keep this medicine? (Back to top)
Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Do not freeze.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Last Updated:May 28, 2007

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